Early Appropriate Diagnostics and Treatment of MDR Gram-negative Infections

A group of global experts from Italy, Lebanon, Thailand, India, the U.S., Colombia and China speak about the need for rapid diagnostic tests and efficient laboratory workflows for multi-drug resistant (MDR) Gram-negative infections. They encourage the adoption of tools like molecular genotyping and antimicrobial susceptibility testing (AST) in the hospital and the outpatient setting to support evidence-based patient care and slow the spread of antimicrobial resistance. They conclude that identification of specific resistance mechanisms would have a major impact on reducing the frequency and duration of inappropriate early antibiotic therapy.

Matteo Bassetti, MD, PhD, Professor of Infectious Diseases at the University of Genoa, Italy

JAC Antimicrobial Resistance
October 1, 2022